REVIEW PAPER
Potential anticancer properties of berries from organic production – a review
 
More details
Hide details
1
Warsaw University of Life Sciences (WULS-SGGW), Faculty of Human Nutrition and Consumer Sciences, Department of Functional Food, Ecological Food and Commodities ul. Nowoursynowska 159C, 02-776 Warszawa, Poland
 
 
Journal of Research and Applications in Agricultural Engineering 2018;63(2):106-108
 
KEYWORDS
ABSTRACT
Berries belong to the best dietary sources of bioactive compounds, mainly phenolic compounds (phenolic acids, flavonoids including anthocyanins and flavonols, tannins) and vitamin C (ascorbic acid). These compounds, either individually or combined, are responsible for various health benefits of berries, in that protective effects to lower the risk of various cancers. Over the last 25 years, a significant number of research studies have compared the contents of phenolics and vitamins, nutritionally relevant minerals, toxic metals, pesticide residues and macronutrients in crops from organic and non-organic production systems. The most recent meta-analysis summarizing the results of 343 peer-reviewed studies comparing plant food from organic and conventional production concluded that organic products are, on average, characterized by significantly higher concentrations of various antioxidants (i.e. phenolic compounds) and much lower incidence of pesticide residues than their conventional comparators. This finding suggests that berries from organic production may have a grater health effects than non-organic ones. In this paper research on anticancer properties of berries and their bioactive compounds is reviewed.
REFERENCES (25)
1.
Baranski M., Średnicka-Tober D., Volakakis N., Seal C., Sanderson R., Stewart G.B., Benbrook C., Biavati B., Markellou E., Giotis C., Gromadzka-Ostrowska J., Rembiałkowska E., Skwarło-Sońta K., Tahvonen R., Janovská D., Niggli U., Nicot P., Leifert C.: Higher antioxidant and lower cadmium concentrations and lower incidence of pesticide residues in organically grown crops: a systematic literature review and meta-analyses. British Journal of Nutrition, 2014, 112(5), 794-811.
 
2.
Battino M., Beekwilder J., Denoyes-Rothan B., Laimer M., McDougall G.J., Mezzetti B.: Bioactive compounds in berries relevant to human health. Nutrition Reviews, 2009, 67 (Suppl. 1), 145-150.
 
3.
De Castro D., Teodoro A.J.: Anticancer properties of bioactive compounds of berry fruits - a review. British Journal of Medicine and Medical Research, 2015, 6(8), 771-794.
 
4.
Del Rio D., Rodriguez-Mateos A., Spencer J.P., Tognolini M., Borges G., Crozier A.: Dietary (poly)phenolics in human health: structures, bioavailability, and evidence of protective effects against chronic diseases. Antioxidants & Redox Signaling, 2013, 18(14), 1818-1892.
 
5.
Diaconeasa Z., Leopold L., Rugină D., Ayvaz H., Socaciu C.: Antiproliferative and antioxidant properties of anthocyanin rich extracts from blueberry and blackcurrant juice. International Journal of Molecular Sciences, 2015, 16, 2352-2365.
 
6.
Faria A., Calhau C., de Freitas V., Mateus N.: Procyanidins as antioxidants and tumor cell growth modulators. Journal of Agricultural and Food Chemistry, 2006, 54(6), 2392-2397.
 
7.
García-Lafuente A., Guillamón E., Villares A., Rostagno M.A., Martínez J.A.: Flavonoids as antiinflammatory agents: implications in cancer and cardiovascular disease. Inflammatory Research, 2009, 58, 537–552.
 
8.
Ghasemzadeh A., Ghasemzadeh N.: Flavonoids and phenolic acids: Role and biochemical activity in plants and human. Journal of Medicinal Plants Research, 2011, 5, 6697-6703.
 
9.
Gross G.G., Hemingway R.W., Yoshida T., Branham S.J.: Plant polyphenols 2. Chemistry, biology, pharmacology, ecology. Proceedings of the 3th Tannin Conference 14-19 of July 1998. Publishers Kluwer Academic Plenum, New York. ISBN 0-306- 46218-4.
 
10.
Hallmann E., Piotrowska A., Świąder K.: The effect of organic practices on the bioactive compounds content in strawberry fruits. Journal of Research and Applications in Agricultural Engineering, 2016, 61(3), 176-179.
 
11.
Hallmann E., Średnicka-Tober D., Kazimierczak R., Rembiałkowska E.: The content of bioactive compounds in different berry fruits from organic and conventional production. [In:] Rahmann G. et al.(eds.) Proceedings of the Scientific Track: Innovative Research for Organic Agriculture 3.0, Organic World Congress 2017 in New Delhi, India, 608-611.
 
12.
Labrecque L., Lamy S., Chapus A., Mihoubi S., Durocher Y., Cass B., Bojanowski M.W., Gingras D., Béliveau R.: Combined inhibition of PDGF and VEGF receptors by ellagic acid, a dietary-derived phenolic compound. Carcinogenesis, 2005, 26(4), 821-826.
 
13.
Manach C., Scalbert A., Morand C., Rémésy C., Jimenez L.: Polyphenols: food sources and bioavailability. American Journal of Clinical Nutrrition, 2004, 79, 727-747.
 
14.
McDougall G.J., Ross H.A., Ikeji M., Stewart D.: Berry extracts exert different antiproliferative effects against cervical and colon cancer cells grown in vitro. Journal of Agricultural and Food Chemistry, 2008, 56(9), 3016-3023.
 
15.
Paredes-López O., Cervantes-Ceja M.L., Vigna-Pérez M., Hernández-Pérez T.: Berries: improving human health and healthy aging, and promoting quality life - a review. Plant Foods for Human Nutrition, 2010, 65, 299-308.
 
16.
Silva L.F., Escribano-Bailón M.T., Pérez J.J., Rivas-Gonzalo J.C., Santos-Buelga C.: Anthocyanin pigments in strawberry. LWT – Food Science and Technology, 2007, 40, 374-832.
 
17.
Somasagara R.R., Hegde M., Chiruvella K.K., Musini A., Choudhary B., Raghavan S.C.: Extracts of Strawberry Fruits Induce Intrinsic Pathway of Apoptosis in Breast Cancer Cells and Inhibits Tumor Progression in Mice. PLoS ONE, 2012, 7(10), e47021.
 
18.
Sporn M.B., Suh N.: Chemoprevention of cancer. Carcinogenesis, 2000, 21, 525-530.
 
19.
Thomasseta S., Berry D.P., Cai H., West K., Marczyło T.H., Marsden D., Brown K., Dennison A., Garcea G., Miller A., Hemingway D., Steward W.P., Gescher A.J.: Pilot study of oral anthocyjanins for colorectal cancer chemoprevention. Cancer prevention research, 2009, 2, 625-633.
 
20.
Vanamala J., Reddivari L., Radhakrishnan S., Tarver C.: Resveratrol suppresses IGF-1 induced human colon cancer cell proliferation and elevates apoptosis via suppression of IGF - 1R/Wnt and activation of p53 signaling pathways. BMC Cancer, 2010, 10, 238.
 
21.
Wahlqvist M.L.: Antioxidant relevance to human health. Asia Pacific Journal of Clinical Nutrition, 2013, 22(2), 171-176.
 
22.
Wang S.Y., Lewers K.S.: Antioxidant activities and anticancer cell proliferation properties of wild strawberries. Journal of the American Society for Horticultural Science, 2007, 132, 647-658.
 
23.
Zhang Y., Seeram N.P., Lee R., Feng L., Heber D.: Isolation and identification of strawberry phenolics with antioxidant and human cancer cell antiproliferative properties. Journal of Agricultural and Food Chemistry, 2008, 56(3), 670-675.
 
24.
Zhang Z., Knobloch T.J., Seamon L.G., Stoner G.D., Cohn D.E., Paskett E.D., Fowler J.M., Weghorst C.M.: A black raspberry extract inhibits proliferation and regulates apoptosis in cervical cancer cells. Gynecologic Oncology, 2011, 123(2), 401-406.
 
25.
Young J.E., Zhao X., Carey E.E., Welti R., Yang S.S., Wang W.: Phytochemical phenolics in organically grown vegetables. Molecular Nutrition & Food Research, 2005, 49, 1136-1142.
 
eISSN:2719-423X
ISSN:1642-686X
Journals System - logo
Scroll to top